Quote and trivia .rss2/19/2024 We also asked him about other lipid-lowering medications known as PCSK-9 inhibitors. Nissen's big study demonstrates that bempedoic acid has important health consequences as well as lowering cholesterol. Other Drugs Used in Cutting Edge Cardiology: Dr. This is what we call the "Number Needed to Treat," or NNT. According to the researchers, 43 people would need to take Nexletol for that time so that one person could avoid a serious outcome. For them, Nexletol significantly reduced the chance of cardiovascular complications compared to placebo. More than 4,000 volunteers didn't have heart disease at the start of the study. These were people who found statins challenging, so Nexletol was the only cholesterol-lowering therapy they used during 40 months of the trial. Nissen and his colleagues conducted a world-wide study of nearly 14,000 people at high risk for cardiovascular events like heart attacks (JAMA, July 11, 2023). Initially, they were encouraged to add a prescription for Nexletol if a patient did not get enough response from a statin alone. Is Nexletol the Next Thing for Lowering Cholesterol? The FDA approved Nexletol in 2020, and doctors have been wondering how best to use it. Steve Nissen, describes the advantages of a relatively new drug called bempedoic acid (Nexletol). Others need more cholesterol-lowering power than a statin can provide. Some people find that they cause side effects that may be intolerable. However, not everyone is able to benefit from a statin. What else does cutting edge cardiology have to offer? Cutting Edge Cardiology Goes Beyond Statins: Statins such as atorvastatin (Lipitor), rosuvastatin (Crestor) or simvastatin (Zocor) are quite effective at lowering cholesterol. If they have been high, you may be taking a statin cholesterol-lowering drug to get them down. Perhaps you also plan for regular checkups and know what your cholesterol levels are. When you think of preventing heart disease, what comes to mind? We hope you envision regular exercise and a healthful diet (whatever that means to you).AugShow 1353: Cutting Edge Cardiology from a Top Heart Doctor
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